In pharma a deal dies not from a “no” but from silence, a forgotten address and a contact who moved on.

In one paragraph

Picture a sales assistant who works out who is worth writing to today and why, drafts the email in the rep's voice and puts it on the desk. The rep only taps “send” or “skip” — the system handles everything else.

Where clients come from — a funnel that runs in a loop

  1. Signal
  2. Person
  3. Email
  4. Reply
  5. Control
  1. 01 · Signal

    Budgets are announced in public.

    Funding, clinical and regulatory milestones, new science and company news are announced in public — each one is a reason to write while it is still news.

    How it works end to end — from trigger to reply, and back01 / 05

    Four engines — one system

    RADAR

    trigger in a registry → company → person

    REACTIVATION

    deals that went quiet a short sequence, no repeats

    COLD OUTREACH

    no conversation yet its own daily cap

    AUTO MODE

    email with no rep tap where accuracy is proven

    the four engines share one database of people, one “do not contact” list, the same pre-send checks and one report — and have separate caps, so none can crowd out another

  2. 02 · Person

    One database of people — one state per person.

    The right person behind the event, found. The four engines cannot overwrite each other's decisions, and a lead is never “paused” and “in a sequence” at the same time.

    How it works end to end — from trigger to reply, and back02 / 05

    One database of people — one state per person

    • “do not contact” list is shared
    • one person — one touch
    • other people's deals are never touched

    What the system remembers about this person

    • meeting notes
    • past correspondence
    • our email history
    • LinkedIn conversation
  3. 03 · Email

    An email that is visibly for this person.

    Written from meeting notes, correspondence, touch history and the LinkedIn conversation — sent from the rep's own mailbox, in the same thread.

    How it works end to end — from trigger to reply, and back03 / 05

    Draft email in the rep's voice

    • approved facts only
    • no repeats within a sequence
    • text from leads is treated as data, not as commands

    Email from the rep's mailbox · LinkedIn message

    • in their name, in the same thread
    • in the rep's own LinkedIn conversation, in their name

    two channels take turns with a lead, never at the same time

  4. 04 · Reply

    Every reply has an action.

    Every reply has its action — a meeting, a pause with a date, a stop, a hand-off to a colleague, a deal in the CRM. No reply — the next email; after the sequence, a rest, and a new trigger brings the person back. Nobody disappears in silence.

    How it works end to end — from trigger to reply, and back04 / 05

    Reply → its own action

    • meeting
    • pause with a date
    • stop, no more emails
    • hand to a colleague
    • deal in the CRM

    ↺ the person's state updates: pause · stop · colleague

    ↺ no reply — next email in the sequence

  5. 05 · Control

    The rep decides. The gates check.

    Signature, address and unsubscribe line; did we write recently; is the address live; the daily cap. Big Pharma and strong signals always go through a human.

    How it works end to end — from trigger to reply, and back05 / 05

    Pre-send checks (gates)

    • signature, address, unsubscribe
    • did we write recently
    • is the address live
    • daily cap

    Card with the rep: send · skip · bad text

    • Big Pharma and strong signals — always through a human

Signals of new budget and new work

you write exactly when a company has just received budget or new work — not to “check in”

01 · RADAR

Research funding

a new research grant — budget for exactly the work you do

02 · RADAR

Financing rounds

the company has just raised money — the budget has just appeared

03 · RADAR

Clinical milestones

a new trial or a move to the next phase

04 · RADAR

Regulatory decisions

a regulator's decision on a drug or an application

05 · RADAR

Patents and publications

new science that shows where a program is heading

06 · RADAR

Hiring for new programs

a team hiring for new work — a contractor is often needed before the hires arrive

Example

a biotech wins a grant to develop a compound. Soon after the award is published, the rep has a card with an email to that company's chief scientific officer

How an email is written — in your rep's voice

an email that is visibly for this person, not a mass mailing; the rep only edits or taps

Example

on a call you agreed to send a proposal — the email opens with exactly that, not with “just checking in”

01

Meetings

call notes: what was discussed, what was agreed, what is still on you — the strongest reason to write

02

Correspondence

all previous email with the person, so the new email continues the conversation instead of restarting it

03

Touch history

what we already wrote and how the person replied

04

LinkedIn conversations

what has already been said in the other channel — so the email does not repeat it and does not read like a stranger's

No repeats

each new email is written to avoid the opener, angle and question of every earlier one in the sequence

Approved facts only

figures and claims about your company come from a single list kept by a human; what is not on it is not written

Every reply gets an action

the rep only sees what needs a human; pauses, do-not-contact entries and return dates happen on their own

01

Agreed to a meeting

names a time, books or gives a phone number → alert the rep immediately

02

Interested, nothing specific

“sounds good”, “I'll check my calendar” → the sequence pauses, the decision is the human's

03

To a colleague

“talk to X” → contact swap

04

“Not now” or budget frozen

→ a pause with a date; the lead comes back on its own

05

Decline

“not relevant for us”, “we're covered” → stop and do-not-contact

06

Question about services or price

→ straight to the rep

07

Left the company

→ a search for the successor in the same role

08

Project closed or went elsewhere

→ the reason for the loss is recorded

Mechanics that save the deal — the cases where money is usually lost

01

A new deal from a reply

someone replied on LinkedIn — a deal is created in the CRM immediately, with an owner and a stage

02

Someone else is writing

a different person answers in the same thread — the system shows who actually runs the matter and stops emails to the silent address

03

The one who passed you on comes back

the lead referred you to another company — later they return to the desk on their own, with that conversation as the opener

04

Pause with a date

“later” and “left the company” each get their own return date · “I'll take it” — the machine steps back. No “forgotten for good”

05

A blocked lead with a live deal

every week — a list of people we no longer contact but whose deal is still open, with its value; the decision is the human's

06

The address was never found

no address was found — the system keeps retrying on its own, and if it still fails, hands the lead to a person

Reliability — what you don't see in a demo

you can't see it in a demo, but it is what decides whether the system still works a year from now without manual supervision

1.3×

failure-handling steps for every working step

For every working step there are 1.3 steps that handle failure — more for failure than for the work itself

measured September 2026

Repeats are recognized

every action carries a fingerprint, so a repeated signal, email or reply is recognized and skipped

A provider outage doesn't burn an attempt

an outside service went down — the lead keeps its chances; the system waits and resumes

Nothing loops forever

every retry has a ceiling; once reached, the record moves to a named final state with a reason and an alert to a human

The safety net — for high-value contacts

a pharma lead can be worth a large contract, and your domain's reputation even more

Example

the rep tapped “send” on an older card — the system re-read the deal: closed → the email does not go out

No credentials, no email

the gates require a signature, a title, the company's postal address and an unsubscribe line

Shared do-not-contact list

anyone on your do-not-contact list — unsubscribed, declined or erased — gets no Catalyst email; one list for every engine

Data erasure requests

the system recognizes such an email on its own, logs it and raises the alarm well before the legal deadline

No attachments, fenced-off text

files are never attached automatically; the lead's text is given to the model as data, with an instruction never to follow commands inside it

Sending cap + pause key

sending is capped over a rolling week; one key pauses outgoing email within seconds

Address check before every email

external deliverability verification: an address that fails the check gets no email, so far fewer bounces reach your domain

Registries give a trigger, not an addressee

a public record tells us when to write; the person to write to is found and verified separately, and we do not use contact details published in the record

You switch the system on yourselves

on the platform, everything specific to you — texts, signature, sources, limits, schedules — lives in settings, not in code; checking on the work needs no access to your mailbox or database

Two or more reps

every lead has an owner; if a second rep reaches for a company already in work, they see a warning first — or you can make it a hard block; lead handover has a set path

Shared limits, separate quotas

channel limits are shared by the team — they protect the domain; daily card quotas are separate per engine

The market — and how the money works

grants, trials and approvals are dated public events with a company behind each one

42,966

new clinical studies registered in 2025

ClinicalTrials.gov · by first-posted date · counted 13 Sep 2026

65,888

NIH-funded projects in fiscal year 2025

NIH RePORTER · sub-projects excluded · counted 13 Sep 2026

46

novel drugs approved by the FDA in 2025

FDA Center for Drug Evaluation and Research · Novel Drug Approvals for 2025 · checked 13 Sep 2026

Research outsourced to CROs — $69.6–85.4 billion in 2025. Development and manufacturing outsourced to CDMOs — $197.4–258.9 billion.

published estimates for 2025: Precedence Research (Feb–Mar 2026), MarketsandMarkets (Apr 2026), Mordor Intelligence (Sep 2026)

Your quiet pipeline

Enter two numbers — the result stays in your browser

Catalyst's reactivation works exactly this list: a short sequence in the rep's voice, a pause with a date for “not now”, a stop for “no”. No forecast here — only your numbers.

How the money works

One subscription

the platform, the four engines and the cost of running them come in one subscription — run it yourself, or have us run it for you

Your providers, your accounts

AI, mailbox and CRM run on your own accounts and keys, and you pay them directly — we resell no data and no model access

Standard

your own isolated workspace on the platform, hosted in the European Union

Premium

a dedicated environment for your company alone — owned and paid for by you

The questions a buyer asks first

short answers about your data; the full terms go into the data processing agreement we sign with every client

01Whose data is it?

Yours. Every lead, email, note and reply belongs to your workspace. On the platform, you can have a full export at any time in a standard database format — ask us and we deliver it.

02Can another client see our leads?

On the platform, the database itself enforces the boundary, not only the app: every record is tied to your workspace, and isolation tests try exactly that — one client reading another’s data.

03Where is the data stored?

On the platform, your database is hosted in a European Union region, where the provider stores and primarily processes it. Providers that process your data are listed by category on the subprocessors page; clients receive the named list and advance notice of changes under the data processing agreement.

04Who sends the emails?

Your rep, from their own mailbox, in the same thread. Nothing goes out from a shared Kason address, and each client sends only from its own accounts.

05What happens when we leave?

You take a full export of your data. And when someone leaves your team, their leads are handed over along a documented path — nothing is lost in a chat.

06Someone asked to be erased — then what?

The system recognizes the request on its own and raises an alarm well before the legal deadline. The erasure is completed within the legal deadline; only a minimal record of the refusal is kept, so the address is not written to again.

07Can we stop everything at once?

Yes — one key pauses Catalyst’s outgoing email within seconds, and sending is capped over a rolling week.

Design partners, not a waiting list.

We work with a small number of CRO and CDMO teams at a time — each shapes the platform and runs it first. Run it yourself, or have us run it for you.

Security · how data is handled · subprocessors · privacy

Catalyst · four engines: reactivation + follow-ups · RADAR · cold outreach · auto mode

your CRM and your reps’ mailboxes stay yours · your data can be exported in full at any time